Many European users prefer to have their computer in English (US). Generally American English is used more than than British English. However with English US on computers, it automatically sets the time format to MM/DD/YYYY and AM/PM clock.
Many non English users prefer to use DD/MM/YYYY with a 24 hour clock. When I adjusted this in Gnome settings, I had to choose British English to achieve this. Windows has an excellent solution for this adding a time format called English(Europe). I don’t think this is very hard to add to Gnome, I believe KDE already has it. That being said, KDE’s settings for formats is a mess and I believe Gnome does this much better. I hope the English(Europe) format can be added in the future to Gnome.
Aside from the DD/MM/YYYY format and 24 hour clock do you specifically want the names of days and months to be in English?
I ask because since GNOME 45, or maybe it was 46, you can configure formats separate from language. So you could set language to English and formats to your own country. That would give you your native date and time format but with the names of days and months not in English.
fwiw, I’m using English(Australia) which happens to be almost 100% sane (date, 24h time, A4 + metric). The only difference to German is that is uses a period for decimal, german uses a comma.