Make sure you have an alpha channel on the layer (Layer > Transparency > Add alpha channel). Layers without an alpha channel have their name in Boldface in the Layers list, other have their name in regular type.
Set the bucket fill tool to Color erase mode, and without a selection, bucket-fill the whole layer with the color to erase.:
But on the whole you should take the habit of drawing the mandala on a transparent layer (itself over a some color/white background). Same visual result, but you can change the color of the background or the mandala very easily: