I understand the implications of upgrading packages while running the desktop, but I wish there was a way (besides dnf upgrade) to take the risk and tell GNOME Software to install them right away.
KDE’s Discover lets you choose which behavior to use: reboot to install (default), or install immediately.
Because I use disk encryption, the two reboots required can be annoying. It usually goes like this: reboot, decrypt disk with passphrase, updates are installed, automatic reboot, decrypt disk again, log in to desktop.
It’s probably easier to do this on shutdown (e.g. before going to bed), so I only have to decrypt once.